Как ни странно, овощи, которые мы употребляем: S. Peterson, Y. Schwarz, S. S. Li, L. Li, I. B. King, C. Chen, D. L. Eaton, J. D. Potter, and J. W. Lampe, “CYP1A2, GSTM1, and GSTT1 Polymorphisms and Diet Effects on CYP1A2 Activity in a Crossover Feeding Trial,” Cancer Epidemiology, Biomarkers & Prevention 18, no. 11 (2009): 3118–25.

В 2010 году Эми Ян из Чикагского университета: A. Yang, A. A. Palmer, and H. de Wit, “Genetics of Caffeine Consumption and Responses to Caffeine,” Psychopharmacology 211, no. 3 (2010): 245–57.

В своей статье в журнале Sleep Ханс-Петер Ландольт: “‘No Thanks, Coffee Keeps Me Awake’: Individual Caffeine Sensitivity Depends on ADORA2A Genotype,” Sleep 35, no. 7 (2012): 899–900.

A2A-рецепторы являются частью биологического пути: S. N. Schiffmann, G. Fisone, R. Moresco, R. A. Cunha, and S. Ferre, “Adenosine A2A Receptors and Basal Ganglia Physiology,” Progress in Neurobiology 83, no. 5 (2007): 277–92.

Нарди пытался лучше понять: A. E. Nardi, F. L. Lopes, A. M. Valenca, R. C. Freire, A. B. Veras, V. L. de-Melo-Neto, I. Nascimento et al., “Caffeine Challenge Test in Panic Disorder and Depression with Panic Attacks,” Comprehensive Psychiatry 48, no. 3 (2007): 257–63.

Нарди доработал тест и провел еще одно исследование: A. E. Nardi, F. L. Lopes, R. C. Freire, A. B. Veras, I. Nascimento, A. M. Valenca, V. L. de-Melo-Neto et al., “Panic Disorder and Social Anxiety Disorder Subtypes in a Caffeine Challenge Test,” Psychiatry Research 169, no. 2 (2009): 149–53.

В 1993 году в письме: H. W. Koenigsberg, C. P. Pollak, and J. Fine, “Olfactory Hallucinations After the Infusion of Caffeine During Sleep,” American Journal of Psychiatry 150, no. 12 (1993): 1897–98.

О еще более странном случае в 2007 году: V. G. Masdrakis, G. Vasilios, N. Vaidakis, E. M. Legaki, D. Ploumpidis, Y. G. Papakostas, and C. R. Soldatos, “Letter to the Editor (Case Report),” Progress in Neuro-Psychopharmacology & Biological Psychiatry 31, no. 7 (2007): 1539–40.

Несколько ученых из Австралии: S. F. Crowe, J. Barot, S. Caldow, J. D’Aspromonte, J. Dell’Orso, A. Di Clemente, K. Hanson et al., “The Effect of Caffeine and Stress on Auditory Hallucinations in a Non-Clinical Sample,” Personality and Individual Differences 50, no. 5 (2011): 626–30.

Один такой случай рассказал доктор Доусон Хеджес: D. W. Hedges, F. L. Woon, and S. P. Hoopes, “Caffeine-Induced Psychosis,” CNS Spectrums 14, no. 3 (2009): 127–29.

В Кентукки в 2009 году Вуди Смит: Douglas Stanglin, “Man Accused of Killing His Wife Set to Use a Caffeine Insanity Defense,” USA Today, September 20, 2010.

Адвокат Ноубла сказал: Wendy N. Davis, “Killer Buzz: Caffeine Intoxication Is Now Evidence for an Insanity Plea,” ABA Journal, June 1, 2011.

10 октября 1859 года доктора Генри Кэмпбелла: H. F. Campbell, “Caffeine as an Antidote to the Poisonous Narcotism of Opium,” Boston Medical and Surgical Journal 63, no. 5 (1860): 101–4. In this paper, Campbell even described a technique for isolating caffeine. A coffee solution was treated with acetate of lead, “sulpheretted hydrogen” (now known as hydrogen sulfide), and ammonia. The product was pure caffeine: “It presents itself in the form of long, silky needles; is fusible, volatile and soluble in water, alcohol and ether.”

В одном исследовании было показано, что у таких детей: B. Schmidt, R. S. Roberts, P. Davis, L. W. Doyle, K. J. Barrington, A. Ohlsson, A. Solimano, and W. Tin, “Caffeine Therapy for Apnea of Prematurity,” New England Journal of Medicine 354, no. 20 (2006): 2112–21.

Теофиллин, родственное химическое вещество: D. J. Henderson-Smart and P. A. Steer, “Caffeine Versus Theophylline for Apnea in Preterm Infants,” Cochrane Database of Systematic Reviews 1 (2010).

Его влияние на головные боли является комплексным: N. Ward, C. Whitney, D. Avery, and D. Dunner, “The Analgesic Effect of Caffeine in Headache,” Pain 44, no. 2 (1991): 151–55; R. E. Shapiro, “Caffeine and Headaches,” Neurological Sciences 28, suppl. 2 (2007): S179–83.

Врачи выяснили, что головные боли: M. Fennelly, D. C. Galletly, and G. I. Purdie, “Is Caffeine Withdrawal the Mechanism of Postoperative Headache?” Anesthesia and Analgesia 72, no. 4 (1991): 449–53.